How can transepidermal water loss be prevented?

• A. By using harsh soaps to cleanse skin.
• B. By applying alcohol-based toners.
• C. By maintaining the natural acid mantle of the skin.
• D. By removing the stratum corneum.

Answer: (C)

Preventing transepidermal water loss hinges on keeping the skin barrier intact, especially the acid mantle that sits at the surface. The acid mantle helps keep lipids in the stratum corneum organized and enzymes working optimally, which together maintain a strong barrier against water loss. When this mantle is preserved, the skin’s natural permeability remains balanced and TEWL is minimized.

Harsh soaps strip away lipids and raise the skin’s pH, weakening the barrier and increasing water loss. Alcohol-based toners can be drying as well, disrupting moisture and barrier function. Removing the stratum corneum would eliminate the primary barrier, causing a dramatic spike in TEWL. Therefore, maintaining the natural acid mantle is the best approach to prevent transepidermal water loss.